The Aging of the American Stomach: Entering the Post-Helicobacter Era?

Physiologic decline occurs in the stomach of every aging human, but pathologic conditions are affected by genetic and environmental factors. Worldwide, the most important of these is believed to be H. pylori-gastritis and its sequelae. However, in the past several decades most industrialized countries, including the United States, have experienced a steady decline in the prevalence of H. pylori. Thus, we hypothesized that the stomach of the American elderly would no longer be dominated by H. pylori-induced pathology.

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