Recognizing the effect of medications

Duodenal epithelium shows marked nuclear pleomophism and mild architectural complexity.

Duodenal epithelium shows marked nuclear
pleomophism and mild architectural complexity.


  • 63-year-old man with a history of colorectal carcinoma and heme-positive stool
  • Biopsy of the duodenum, endoscopically showing mucosal irregularity
  • Histology worrisome for dysplasia/carcinoma. Miraca GI pathologists recognized likely therapy effect
  • Clinician contacted; subsequent chart review revealed previous 5-FU chemotherapy

Our Diagnosis

  • Active Duodenitis with Reactive Epithelial Atypia, Consistent with Chemotherapy Effect

The Miraca Life Sciences Difference

  • No confusion as to whether the patient has a malignant process (primary or metastatic) involving the duodenum
  • No dysplasia or malignancy is present

Choose Miraca for Your Patients

Learn more about Miraca's Anatomic Pathology services

Learn More »
TRADESHOWS >> FIND posters and presentations from past shows, and see where Miraca Life Sciences will be next.

The entire Miraca team has been the most supportive client service team we have ever dealt with. After 18 years as a clinical supervisor with our practice, I have been most impressed with the accessibility and commitment of the entire team to facilitate any and all services available to help grow our practice with the most current tools available. From Amberlyn [Abbott], our sales rep, to Lindsay [Alexander] and Zac [Whaley], our technical support, we have never heard, ‘I don’t know’ or ‘We do not do that.’ They are the most dedicated team to find answers. If they don’t have them, they find them!!
— Brenda Esser, Clinical Supervisor
Parks Dermatology Center, Daytona Beach, Fla.

Learn about Miraca's unmatched quality. We provide our clients with access to the highest quality AP services.
Get news from Miraca. Join our email list.