Malakoplakia

Guy M. Lindberg, Robert M. Genta, M.H. Saboorian, Miraca Life Sciences Research Institute, Irving, TX

Malakoplakia (MP) is a rare granulomatous condition thought to result from the insufficient killing of bacteria by macrophages; it is of uncertain clinical significance and can occur at any tissue site. It may be focal or widespread, involving multiple organs. Gastrointestinal MP has been described in association with a variety of conditions such as ulcerative colitis, diverticulitis, adenomatous polyps, and carcinoma. It has been reported

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