Knowing what isn’t on the slide is as important as what is

Normal villous architecture and surface epithelium. The lamina propria appears normal, but close observation reveals the absence of plasma cells in the lamina propria.

Normal villous architecture and surface epithelium. The lamina propria appears normal, but close observation reveals the absence of plasma cells in the lamina propria.

 

  • 78-year-old woman with chronic diarrhea
  • Upper endoscopy demonstrated numerous small nodules at the duodenal bulb

 

 

 

 

 

Our Diagnosis

  • Absent plasma cells, consistent with an immunodeficiency disorder

Clinician Contacted

  • Patient later confirmed to be IgA deficient

The Miraca Difference

  • Identification of a potentially treatable condition
    • Likely to have been considered “normal” by general pathologists
  • Extremely subtle features recognized that may explain diarrhea, malabsorption, sinopulmonary disease or bacterial infections
  • Information may prevent a reaction to a future blood transfusion

Choose Miraca for Your Patients


Learn more about Miraca's Anatomic Pathology services

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Miraca has made our life much easier by providing the necessary technology, the most professional service and excellent customer service. We have used different pathology labs in the past. Miraca is the most outstanding among all of them.
— Angela Wong, Office Manager, David S. Ho, MD, Urologist
Houston, Texas


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