Identifying subtle histologic findings

Unremarkable-appearingmucosa except for a subtle darkening of the surface that corresponds to microorganisms.

Unremarkable-appearing mucosa except for a subtle darkening of the surface that corresponds to microorganisms.


  • 73-year-old woman presented with diarrhea, weight loss
  • Endoscopic examination revealed an unremarkable colonic mucosa
  • Biopsies taken to exclude microscopic colitis




Our Diagnosis

  • Colonic Spirochetosis

The Miraca Difference

  • Provides a reasonable explanation for this patient’s diarrhea and weight loss (spirochetosis can also cause rectal bleeding, abdominal pain, purulent discharge, and an appendicitis-like picture)
  • Avoidance of complications related to immunosuppressive therapy
  • Identifies a condition that may respond to antibiotic therapy
  • Recognition of a subtle finding that may be easily overlooked

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Learn more about Miraca's Anatomic Pathology services

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We’re pleased with the excellent MU resources that Steve Sharp has provided, and the advocacy he has taken on our behalf. Howard Gervasoni is a true MU SME, helping us to understand the rules and their applicability to us on a pragmatic basis, assisting [with] implementing the compliance mechanics within our practice’s clinical operations, guiding our scorekeeping analytics as we monitored our performance through the measurement periods, testing our IT systems and security as appropriate, and supporting our input submission and validation processes. In addition to technical competence, he has great interpersonal skills—important in helping irritated lay people deal with a perceived “nuisance” endeavor. The “bottom line” is that with Miraca’s help we achieved our MU goals which were of significant consequence to us!
— Morgan Hunnewell, Practice Manager; Ron Drabik, Project Administrator; Dr. Vinod Thakkar, President,
Thakkar, Patel & Avalos, Sebring, Fla.

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