Following up to rectify historically incorrect diagnoses

Active cryptitis and a lymphoplasmacytic infiltrate suggest ulcerative colitis; however, intraepithelial lymphocytosis and maintenance of the crypt architecture betray the correct diagnosis.

Active cryptitis and a lymphoplasmacytic infiltrate suggest ulcerative colitis; however, intraepithelial lymphocytosis and maintenance of the crypt architecture betray the correct diagnosis.

 

  • 18-year-old woman with a clinical history of ulcerative colitis
  • Patient presents with diarrhea

 

 

 

 

 


Our Diagnosis

  • Lymphocytic Colitis

The Miraca Life Sciences Difference

  • Patient’s outside slides were requested and reviewed
    • Our opinion that these outside biopsies (incorrectly interpreted as “Ulcerative Colitis”) also represented Lymphocytic Colitis
  • Avoidance of complications related to immunosuppressive therapy
  • Allows for appropriate therapy for lymphocytic colitis
  • No need for continuance of lifetime colonic surveillance