Biopsy Practice Patterns and Diagnostic Yield in Cases of Suspected Eosinophilic Esophagitis in the United States

Abstract published in Gastroenterology, April 2011

Authors: Robert C. Capel, MD, and Robert M. Genta, MD

For patients suspected of having eosinophilic esophagitis (EoE), published consensus recommendations suggest how esophageal biopsy specimens should be obtained. The aim of this study was to examine current biopsy practice patterns in suspected EoE cases in the United States, and to determine the relationship between location of esophageal biopsies and the histopathologic diagnosis of EoE.

In cases of suspected EoE, when biopsies were submitted from multiple specified locations along the length of the esophagus, vs. a single location, the positive diagnostic yield increased by over three-fold.

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