A Rare (11;22)(q23;q11.2) Translocation in a Patient with Chronic Lymphocytic Leukemia

K. Horvath, K. Webber, E. Hayes, T. Zeliadt, W.L. Flejter PhD – Miraca Life Sciences, Phoenix, AZ

We received bone marrow and peripheral blood samples from a 58-year-old year old female with a clinical indication of chronic lymphocytic leukemia (CLL). Morphology, fluorescence in situ hybridization (FISH), cytogenetics and flow cytometry were performed and compared. The morphological evaluation showed a large number of predominantly small, mature-appearing lymphocytes and smudge cells.

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