FISH Probes

ALL
CEP 4
p16 (9p21) / CEP9
CEP 10
BCR/ABL t(9;22)
MLL (11q23)
TEL/AML1 t(12;21)

MM
CEP 7, CEP 9
CCND1/IgH t(11;14)
Reflex to FGR3/IgH t(4;14)
RB1 (13q14.2)
p53 (17p13.1)

AML
ETO/AML1 t(8;21)
MLL (11q23)
PML/RARA t(15;17)
CBFB inv(16)/t(16;?)
BCR/ABL t(9;22)

NHL
BCL6 (3q27)
c-MYC (8q24)
CCND1/IgH t(11;14)
IgH/BCL2 t(14;18)
MALT1 (18q21)

CLL
ATM (11q22.3)
CEP 12
CCND1/IgH t (11;14)
D13S319 (13q14.3)
p53 (17p13.1)

CML
BCR/ABL t(9;22)
Reflex to ASS1 (9q34.1)

MDS
EGFR1 (5q31)
D7S522 (7q31)
CEP 8
MLL (11q23)
RB1 (13q14.2)
D20S108 (20q12)

MPD
PDGFRA/FIP1L1 (4q12)
PDGFRB (5q33.1)
CEP 8
CEP 9
BCR/ABL t(9;22)

Anaplastic Large Cell Lymphoma
ALK (2p23) t(2;5)

Follicular Lymphoma
IgH/BCL2 t(14;18)

Burkitt's Lymphoma
c-MYC (8q24)

Mantle Cell Lymphoma
CCND1/IgH t(11;14)

Additional Probes
Synovial Sarcoma SYT (18q11.2)
Ewing's Sarcoma ESWR1 (22q12)

Transplant Monitoring
XX/XY for Sex
Mismatched Transplant