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Comprehensive Breast Pathology

Inform Diagnostics offers a full range of testing for breast disease diagnosis and management.

Genetic testing is provided by Baylor Genetics—a joint venture between Baylor College of Medicine and Miraca Holdings. Baylor has provided diagnostics services for more than 35 years and is the no. 1 National Institutes of Health-funded genetics program.

Pathology Services

  • TNM staging per CAP protocols
  • Sentinel lymph node protocols (H&E, IHC)
  • ER/PR/Ki67/HER2 predictive/prognostic testing
  • HER2-FISH/CISH
  • Metastasis confirmation
  • Calcifications confirmation

Genomic Testing Services

  • Recurrence management with additional tests as needed
    • Breast Cancer Gene Mutation Panel (Performed by Baylor Genetics)
    • BRCA1 and BRCA2 Screening (Performed by Baylor Genetics)
    • High Risk Hereditary Breast Cancer Panel (7 genes: BRCA1, BRCA2, CDH1, PALB2, PTEN, STK11, TP53) (Performed by Baylor Genetics)
    • Tamoxifen CYP2D6 Genotype by PCRE-Cadherin (IHC)
    • EGFR (IHC)

NCCN Criteria

National Comprehensive Cancer Network (NCCN) Guidelines support testing for the BRCA1 and BRCA2 genes in patients suspected of hereditary breast and/or ovarian cancer syndromes. Use Miraca’s NCCN Criteria form to help determine if your patient meets criteria in the NCCN Guidelines for genetic risk evaluation of breast and/or ovarian cancer. Miraca often can use this information, in addition to clinical notes, for prior authorization requests.

Insurance and Billing Information for Genomic Testing

We’re pleased with the excellent MU resources that Steve Sharp has provided, and the advocacy he has taken on our behalf. Howard Gervasoni is a true MU SME, helping us to understand the rules and their applicability to us on a pragmatic basis, assisting [with] implementing the compliance mechanics within our practice’s clinical operations, guiding our scorekeeping analytics as we monitored our performance through the measurement periods, testing our IT systems and security as appropriate, and supporting our input submission and validation processes. In addition to technical competence, he has great interpersonal skills—important in helping irritated lay people deal with a perceived “nuisance” endeavor. The “bottom line” is that with Miraca’s help we achieved our MU goals which were of significant consequence to us!
— Morgan Hunnewell, Practice Manager; Ron Drabik, Project Administrator; Dr. Vinod Thakkar, President,
Thakkar, Patel & Avalos, Sebring, Fla.


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